1Department of Veterinary Medicine, College of Veterinary and Animal Science, Navania, Vallabhnagar, Udaipur (Rajasthan), India
2Department of Animal Nutrition, PGIVER, Jaipur, (Rajasthan), India
3Department of Veterinary Public Health, College of Veterinary and Animal Science, Navania, Vallabhnagar, Udaipur (Rajasthan), India
4Department of Veterinary Microbiology, College of Veterinary and Animal Science, Navania, Vallabhnagar, Udaipur (Rajasthan), India
*Corresponding author: RK Khinchi; E-Mail: rakeshkhanna.jjn@gmail.com
Online Published on 19 July, 2023.
Babesia is one of the most common causes of anemia in cattle. The present study was designed to determine the changes in haemato-biochemical parameters and biomarkers of oxidative stress in Babesia infected cattle. Twelve Babesia infected cattle (irrespective of age, sex and breed) were selected for this study. Clinical signs, microscopic findings and PCR findings were recorded and blood samples were collected to investigate the haemato-biochemical parameters and biomarkers of oxidative stress. The most commonly observed symptoms were pyrexia, haemoglobinuria, tick infestation and icteric mucous membrane. Among the haemato-biochemical changes, significant reduction in haemoglobin, PCV, RBC count, albumin and serum glucose along with significant increase in TLC, serum total protein, globulin, ALT, AST, serum total bilirubin and serum creatinine were observed. Assessment of biomarkers of oxidative stress showed significant increase in malondialdehyde (MDA) and total nitric oxide (NO) along with significant reduction in glutathione s-transferase activity (GST activity), catalase and superoxide dismutase (SOD) activities. These findings support the theory that Babesia infection causes oxidative stress, which may be linked to the anaemia.
• Babesia infection caused oxidative stress in cattle.
• Significant increase in malondialdehyde (MDA) and total nitric oxide (NO).
Babesia, Oxidative stress, Anaemia, Haemato-biochemical
