Clinico-haematobiochemical profiling and therapeutic studies on hypophosphatemic dairy buffaloes

The present study was aimed to investigate the clinical, haemato-biochemical profile of hypophosphatemic dairy buffaloes, followed by therapeutic management. The investigation was conducted on 20 dairy buffaloes brought to Veterinary Clinical Complex, LUVAS, Hisar. The study revealed 4-7 years old buffaloes in their early lactation to be most commonly affected and the prominent clinical signs observed were anorexia, hypogalactia, straining during urination and difficulty in walking. Haematology showed significant (P< 0.01) increase in neutrophils count and mean values of ESR. Serum biochemistry revealed significant decrease in serum inorganic phosphorus with non-significant elevation in other biochemical parameters. Animals were randomly allocated into 2 groups. In group I, sodium acid phosphate @120 gm in 600 ml NSS (half dose IV and half SC), followed by same dose orally for 5 days was given along with supportive therapy while in group II, Injection Novizac^R (buffered phosphorous injection) along with supportive therapy was given for 5 days. Based on therapeutic trial, sodium acid phosphate therapy was found to be the most effective in management of hypophosphatemia in dairy buffaloes.