Identification of novel single nucleotide polymorphisms in Myf6 gene associated with myogenesis in large white Yorkshire vis-à-vis non-descript pigs of Punjab

The study focused on the Myf6 gene associated with myogenesis, investigating its genetic variations and evolutionary dynamics in Large White Yorkshire and Non-descript pigs from Punjab. This study focused on the Myf6 gene, a crucial regulator of myogenesis, to explore its genetic variations, evolutionary dynamics, and functional significance across species. Nucleotide sequence analysis revealed novel single nucleotide polymorphisms (SNPs) and indels, with a transversion mutation identified in Non-descript pigs in the intronic region of intron 2, potentially influencing gene expression through intron-mediated regulation. These findings offer genomic selection potential for breeding pigs with desired meat traits. The identified Myf6 variations could serve as markers for efficient breeding, benefiting pig production. Additionally, genetic characterization aids Non-descript pig conservation and management. This study informs Myf6 evolution, breeding strategies, and indigenous breed preservation.

⓿ Focused to identify SNPs in Large White Yorkshire and non-descript pigs.

⓿ Understanding evolutionary perspective of Myf6 gene in divergent species.