1Department of Veterinary Microbiology, College of Veterinary Science & Animal Husbandry, Nanaji Deshmukh Veterinary Science University, Mhow, Jabalpur, Madhya Pradesh, India
2Department of Veterinary Microbiology, College of Veterinary Science & Animal Husbandry, Jabalpur, India
3Department of Veterinary Pharmacology & Toxicology, College of Veterinary Science & Animal Husbandry, Jabalpur, India
4Department of Veterinary Medicine, College of Veterinary Science & Animal Husbandry, Mhow, Madhya Pradesh, India
*Corresponding Author: P. Shakya; Email: drpoonamvet@rediffmail.com
Online published on 24 March, 2014.
To study the immunomodulatory effect of cow urine ark(distillate) and medicinal herbs, evaluation of cell mediated immune (CMI) response by delayed type hypersensitivity(DTH) reaction to 2,4-dinitro chloro benzene (of experiment DNCB) in the broilers of group I(control), group II(ark treated), group III(ark and W. somnifera treated), group IV(ark and T.cordifolia treated), group V(ark, W. somnifera and T. cordifolia treated) and group VI(ImmuPlus-a polyherbal preparation treated) was carried out. The result indicated that DTH reaction in the broilers of group VI was most severe at 24 hours post challenge on 42nd day of experiment than that followed by group V, IV, III, II and I. DTH response indicates that cow urine ark and medicinal herbs are a potent immunomodulatory agent enhancing the cell mediated immune response. One of the explanations forwarded to justify the beneficial effect of cow urine and medicinal herbs in diseased stress is the non specific enhancement of immune status of the individual.
Cell mediated immunity, Delayed type hypersensitivity, Withania somnifera, Tinospora cordifolia
