Journal of Animal Research
  • Year: 2016
  • Volume: 6
  • Issue: 6

Impact of A1/A2 forms of Cow's Milk on Human Health-A review

1Department of Veterinary Surgery and Radiology, Faculty of Veterinary and Animal Sciences, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India

2Division of Veterinary Medicine, Faculty of Veterinary Science & Animal Husbandry, Sher-e-Kashmir university of Agricultural Sciences and Technology of Jammu, R.S. Pura, Jammu, J&K, India

*Corresponding author: NK Singh; Email: naresh2101@gmail.com

Online published on 7 February, 2017.

Abstract

Milk derived peptides may adversely affect the biological health of humans by increasing the risk of dependency on insulin to overcome the occurrence of diabetes. The higher occurrence of the diabetes relies on the relationship of type 1 diabetes (T1D) and the consumption of variants A1 and B beta-casein from cow's milk. T he production of BC M-7 is more in A1 milk than A2 milk and the difference is basically due to position 67 of the beta casein chain. However, proline in A2 is substituted by histidine in A1 milk casein chain. Deleterious effects of A1 milk in the process of digestion in human stomach and intestines have not been reviewed earlier. It is an effort to review the aspect thoroughly and bring minor details into focus to have better understanding of the milk particularly in perspective of human health.

Keywords

A1milk, A2 milk, exotic cows, indigenous cows, proline amino acid, histidine amino acid