In vitro Antioxidant and Antibacterial Efficacy of Condensed Tannins Containing Tree Leaves Extract of Jammu Province

The present study was conducted to assess the antioxidant potential and antibacterial efficacy of lyophilized condensed tannins (CT) extract from locally available tree leaves (Acacia nilotica, Eugenia jambolana, Ficus religiosa, Leucaenea leucocephala and Psidium guajava) against bacterial species (viz. Enterococcus faecalis, Escherichia coli, Salmonella enteritidis and Staphylococcus aureus). Antioxidant activity was determined by 1, 1-Diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging and total reducing power assays. Lyophilized CT extracts of P. guajava and E. jambolana showed significantly (P<0.05) higher antioxidant potential compared to standard ascorbic acid and other CT sources. Antibacterial efficacy was determined by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) using micro dilution method. The MIC and MBC values of CT extracts were significantly (P<0.05) higher for F. religiosa and L. leucocephalla then that of A. nilotica, E. jambolana and P. guajava. The MBC value for S. enteritidis was lower than E. coli and. S. aureus. Lower MIC and MBC values against E. coli, S. aureus and S. enteritidis in CT extracts of different sources showed better results compared to E. faecalis which showed statistically non-significant difference among all CT sources. It may be concluded that all CT sources possess antioxidant and antibacterial efficacy and were found to be effective against E. coli, S. aureus and S. enteritidis except E. faecalis and the comparison among the CT sources, E. jambolana and P. guajava were found to be most potent CT source as well as potent alternative antioxidant and antibacterial agents.