Haemato-Biochemical Comparision of Meloxicam/Ketoprofen in Combination with Atropine-Dexmedetomidine-Butorphanol-Midazolam as Preanasthetic to Ketamine Anaesthesia in Female Dogs

The study was conducted in 12 female dogs undergoing elective ovariohysterectomy divided into two groups of six animals each to evaluate and compare hemato-biochemical findings in meloxicam/ketoprofen along with atropine-dexmedetomidine-butorphanol-midazolam-ketamine anesthetic combination. Adequate muscle relaxation, sedation and analgesia necessary for surgical intervention were achieved along with smooth and uneventful recovery in all patients. Blood samples were collected at 0min (baseline), 15min, 30min, 45min, 60min and 90min for assessment of Hb, TLC, DLC, plasma urea nitrogen and plasma creatinine. Results were non-significant decrease in Hb, increase in plasma urea nitrogen and increase in plasma creatinine in both the groups. TLC showed non-significant decrease up to 30min followed by gradual increase to baseline. Variation in DLC was clinically insignificant. Both meloxicam and Ketoprofen produced a comparable degree of clinico-physiological and haemodynamic stability in atropine-dexmedetomidine-butorphanol-midazolam-ketamine anaesthetic combination in dogs undergoing elective ovariohysterectomy.