1Division of Animal Genetics, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, (UP), India
2ICAR-Directorate of Poultry Research, Rajendranagar, Hyderabad, Telangana, India
3Department of Animal Genetics and Breeding, Sri Venkateswara Veterinary University, Tirupati, Andhra Pradesh, India
*Corresponding author: TK Bhattacharya; Email: bhattacharyatk@gmail.com
Online published on 7 December, 2018.
Acetyl-CoA carboxylase A (ACACA) is a rate limiting enzyme and plays a crucial role in the production of precursors of fatty acid biosynthesis. The objective of this study was to analyse the expression levels of ACACA at different ages of juvenile stage in one control layer (CL) chicken strain. As the birds are slow growing, the expression of the gene exhibited an increasing trend. A negative correlation has been found between body weight and mRNA expression of the gene at 6 weeks of age indicating complete utilization of energy for growth. When compared to day 1 expression, gene expression was up-regulated by 1.5, 10.5 and 10.8 folds at day 14, 28 and 42 of the birds, respectively. It is concluded that the expression of ACACA gene was increased gradually as age progressed during juvenile stage in layer chicken.
Fatty acid biosynthesis, Acetyl-CoA carboxylase A, ACACA, mRNA levels
