1Department of Medicine, Bombay Veterinary College, Parel, Mumbai - 400 012.
2Bombay Veterinary College, Parel, Mumbai - 400 012
3Department of Veterinary Nuclear Medicine, Mumbai-400 012.
4Institute of Immunohematology, KEM Hospital, Parel, Mumbai-400 012.
Department of Medicine Bombay Veterinary College, Parel, Mumbai - 400 012.
* Part of M. V. Sc. Thesis submitted by the first author to Maharashtra Animal and Fishery Sciences University, Nagpur.
This paper presents the efficacy of fresh and fresh frozen plasma in disseminated intravascular coagulation (DIC) cases in dogs. DIC is common acquired coagulapathy in dogs. In the present study total 6 dogs were diagnosed on the basis of signs and increased CBCT, ACT, PT, aPTT, TT, FDPs and decreased plasma fibrinogen and presence of D-dimer. The therapeutic management of DIC by replacement of coagulation factors, proteins and fibrinogen was studied with the improvement in coagulation parameters. The before and after treatment values of CBCT was (9.01 ± 1.05 and 6.23 ± 0.34 min), ACT (140.83± 10.68 and 118.33 ±6.88 sec), PT (17.33 ± 4.17 and 14.16 ± 0.75 sec), aPTT (20.00 ± 3.46 and 15.50 ± 1.76 sec), TT (31.00 ± 8.27 and 20.66 ± 2.50 sec), FDPs (5–20 mg/dl), fibrinogen (193.00 ± 61.48 and 260.00 ±73.76 mg/dl) and presence of D-dimer. All coagulapathy tests were significantly improved after administration of fresh and fresh frozen plasma.
DIC, FFP, fresh plasma and D-dimer
