18 clinical cases of dogs presented for different surgeries of hind quarter, castration, spaying, hernioraphy, etc. were randomly divided into 3 groups of 6 dogs in each. Epidural analgesia was induced by injecting bupivacaine hydrochloride (2mg/kg) in group-I, xylazine hydrochloride (1mg/kg) in group-II and xylazine hydrochloride (0.5mg/kg) and bupivacaine hydrochloride (1mg/kg) in group-III into the lumbosacral space. A significant reduction in heart rate and rectal temperature was recorded in all the three groups but it was more in group-II and III than group-I. Respiratory rate showed a significant decrease in group-II and III; however, no significant change was noted in group-I. A significant fall in mean systolic blood pressure from 5–60 minutes of analgesia in group-III, whereas no significant alterations were recorded in group-I. A progressive and irregular decrease in mean diastolic blood pressure was recorded during analgesia in group-I and II; however, no significant alteration was recorded in group-III.
