A total of six clinical cases of cats, presented for major surgical procedures at Bombay Veterinary College were utilized for this study. Following the standardization of induction dose and maintenance dose, a clear solution of propofol was administered intravenously at the rate of 10 mg/kg body weight over the period of 60 – 70 seconds in each cat. Longer duration of surgical anaesthesia was maintained by continuous infusion rate of propofol solution at the dose rate of 0.25 mg/kg/min in all the cats. Onset of anaesthesia, duration of anaesthesia, and recovery were assessed for each cat. The physiological parameters before induction, 5, 15, 30, 45, 60 minutes during maintenance of anaesthesia & following complete recovery were recorded for each cat. The onset of anaesthesia, duration of anaesthesia and complete recovery recorded were 23.5 ± 1.6 seconds, 48.33 ± 4.5 minutes and 83.33 ± 12.37 minutes respectively. A significant decrease in body temperature and respiratory depression was observed during the anaesthesia where as a significant increase in heart rate and pulse rate were recorded during the anaesthesia. However, all the values were in normal physiological limits.
