Journal of Camel Practice and Research
SCOPUS
  • Year: 2014
  • Volume: 21
  • Issue: 2

Effect of enrofloxacin on hepatic microsomal mixed function oxidases in camel

Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine and Animal Resources, King Faisal University, PO Box 400, Al-Ahsa, 31982, Saudi Arabia

*Email: malnazawi@kfu.edu.sa

Online published on 26 May, 2015.

Abstract

Administration of enrofloxacin at a dose of 5 mg/kg intramuscularly for 3 days has resulted in a significant decrease in aminopyrine-N-demathylase and aniline-4-hydroxylase in liver of camel compared to saline treated (controls). It is suggested that co-administration of drugs metabolised by phase-I reaction with enrofloxacin should be avoided in camels.

Keywords

Camel, enrofloxacin, hepatic, oxidases