Camel milk alleviates alcohol induced liver injury in mice

The present study aimed to investigate the effectiveness of camel milk (CM) in alleviating alcohol-induced hepatotoxicity as a model of clinical liver illness. Male mice were divided into 4 groups: pair-fed control (PE), ethanol (ET), camel milk treated group (CM) and cow milk treated group (NM). Mice from the PE ingested a Lieber-DeCarli controls liquid diet, while mice from the ET, CM and NM groups ingested a Lieber-DeCarli alcohol liquid diet of 8 weeks. Camel milk and cow milk were orally administered from the beginning of the 4^th week until the end of the experiment. Mice from camel milk group was observed to significantly reduce the levels of serum ALT, AST and LPS compared with other groups. The hepatic steatosis was improved after camel milk administration and attenuated alcohol-induced oxidative stress by declining the level of hepatic oxidants. In addition, the production of apoptosis was inhibited by preventing the formation of TNF-a in the CM group. These results showed that camel milk may alleviate alcohol-associated hazards and protect hepatic tissue from alcohol-induced toxicity.