1Department of Anatomy and Histology, Faculty of Veterinary, Animal and Biomedical Sciences, Khulna Agricultural University, Khulna, Bangladesh
2Department of Anatomy and Histology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
3Department of Pathology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
Department of Anatomy and Histology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
*Corresponding Author: Swarup Kumar Kundu, Department of Anatomy and Histology, Faculty of Veterinary, Animal and Biomedical Sciences, Khulna Agricultural University, Khulna, Bangladesh, Email: swarupkundu@kau.edu.bd
Online published on 19 July, 2021.
Organ meats are rich in cholesterol and saturated fats. The experiment was conducted to investigate the effects of cow brain consumption on blood cholesterol level and possible histomorphological changes of liver, heart and kidney in Swiss albino mice.
Total twenty (20) Swiss albino mice (aged 3 weeks; average weight 20-25gm) were taken and randomly divided into group A and group B. Each group consisted of ten (10) mice. The group A was fed with normal mice pellet and water. On the other hand, cow brain (2gm/kg body weight orally once daily for 28 days) was supplied to group B. After the experimental tenure, the mice of both groups were sacrificed ethically and the samples (Blood, liver, heart and kidney) were collected for investigation.
Total cholesterol (TC), triglyceride level (TG) and low density lipoprotein level (LDL) significantly (**p<0.01) increased as well as high density lipoprotein level (HDL) significantly (**p<0.01) decreased in group B. In the gross observation, pale with hemorrhagic liver, fat accumulation at the base of the heart and peri renal fat deposition were found in group B of mice. Congestion and dilation in both central and portal vein, marked lymphocytic infiltration and fatty infiltration in liver, wide separation of cardiac muscle fiber in ventricular myocardium, glomerular and tubular fatty infiltration of kidney were also found in histomorphological study. Therefore, the present findings presage that cow brain consumption might have baleful effects on health.
Cow brain, Health risk, Hypercholesterolemia, Pathological changes, Swiss albino mice
