Comparative Study of Xylazine-ketamine and Xylazine-tramadol as General Anesthetic Agents in Cats

The appropriate selection and administration of anesthetic agents are paramount for ensuring both the safety and efficacy of surgical and diagnostic procedures in feline patients. This study was designed to evaluate incidence of onset time, efficacy, safety and side effects in using of Xylazine-Ketamine and Xylazine-Tramadol as general anesthetic agents in cats.

Ten adult female and male cats of a parentally health in both group, the experimental animals were divided randomly into two equal groups: five cats for each group: First group (n= 5): was given (2%) Xylazine hydrochloride as sedative agent at dose (1) mg/kg I.M followed by I.M injection of 100% Ketamine at dose (20) mg/kg. while, Second group (n=5): was given Xylazine at dose (1) mg/kg I.M followed by I.M injection of (5%) tramadol at dose of (1) mg/kg. The parameters which were used for evaluation included heart and respiratory rates, rectal body temperature. The clinical parameters included induction time, eye reflex, recovery time, muscle relaxation after induction of anesthetic drug. The parameters which were used for evaluation included heart and respiratory rates, rectal body temperature. The clinical parameters included induction time, eye reflex, recovery time, muscle relaxation after induction of anesthetic drug.

Physiological parameters showed no-significant changes in both the groups; the induction time started after three to five minutes in first group, while in the second group after five minutes from administration of Xylazine-Tramadol. The recovery was smooth in both the groups, muscle relaxation was excellent in first group and good in second group and was does dependent. The eye reflex was absent in Xylazine-Ketamine group, while in the second group was variable.