Journal of Dental and Orofacial Research
  • Year: 2016
  • Volume: 12
  • Issue: 2

Immunohistochemistry: A Brief Review

  • Author:
  • K. Shwetha Nambiar1,, Vanishree C. Haragannavar2, Dominic Augustine2, S. V. Sowmya3, Roopa S. Rao4, Karuna Kumari5, V. Pavithra5
  • Total Page Count: 5
  • Page Number: 25 to 29

1Tutor, Department of Oral Pathology, Faculty of Dental Sciences, RUAS, Bangalore

2Senior Lecturer, Department of Oral Pathology, Faculty of Dental Sciences, RUAS, Bangalore

3Senior Lecturer, Department of Oral Pathology, Faculty of Dental Sciences, RUAS, Bangalore

4Professor, Head Of Department Department of Oral Pathology, Faculty of Dental Sciences, RUAS, Bangalore

5Post Graduate students, Department of Oral Pathology, Faculty of Dental Sciences, RUAS, Bangalore

*Corresponding Author Email: drshwethas83@gmail.com

Online published on 18 January, 2019.

Abstract

Immunohistochemistry (IHC) is a technique for identifying cellular or tissue constituents (antigens) by means of antigen-antibody interactions. It is useful as an auxillary diagnostic procedure in histopathology. The introduction of prognostic and predictive markers in IHC has made a tremendous impact on patient's treatment and management. These methods are particularly useful to a pathologist in ambiguous areas of neoplastic process enhancing the accuracy to large extent. This review provides a summary of merits, demerits, staining procedures and troubleshooters in immunohistochemistry technique.