1Assistant Professor, Government Dental College, Vandanam, Alappuzha, Kerala
2Professor and Head, Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054
3Post Graduate Student, Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054
4Associate Professor, Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bengaluru-560054
5Associate Professor, Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia
*Corresponding Author Email: sowmya.op.ds@msruas.ac.in
Online published on 18 January, 2019.
Non syndromic cleft lip with or without cleft palate (NSCLP) is one of the most common birth defects. If genetic predisposition of individuals towards cleft lip can be detected, it can improve its prediction rate. Hence, this study was conducted to assess the specific pattern of lip prints in patients and parents of NSCLP. The study was also investigated to know whether any specific pattern of lip print exists in patients and in their accompanying parents, which can aid in predicting the risk of incidence of cleft lip and palate.
100 patients with NSCLP, and their accompanying parents attending Mahaveer Jain Hospital, M.S. Ramaiah Dental College and Hospital, Bangalore and Smile Train Centre at Jubilee mission hospital, Kerala were selected for the study. Lip print analyses were done and the data was statistically analysed using Chi-square test.
17% of NSCLP patients and 32% of parents showed whorl type lip prints. There was no statistically significant difference in the incidence of whorl type pattern among patients from different states (p = 0.721). Statistically significant difference was not observed in the incidence of whorl type pattern among parents from different states (p =0.377). Parents showed significantly higher incidence of whorl type pattern as compared to NSCLP patients (p = 0.0213).
The whorl type lip print pattern varied between patients and parents of NSCLP without any state-wise differences. Parents showed significantly higher incidence of whorl type pattern. As majority of parents of NSCLP patients had whorl type pattern, it may be considered as an extended phenotype of NSCLP.
Lip Prints, Non Syndromic Cleft Lip With or Without Cleft Palate, Whorl Type Pattern