Central Giant Cell Granuloma Involving Mandible-A Report with CT Findings

Central Giant Cell Granuloma (CGCG) involving either jaw is not a common benign intra-osseous lesion containing giant cells; characterized by osteoclast-like giant cells in a cellular fibrovascular stroma. The true nature of this lesion is controversial and remains unknown: the three competing theories are that it could be reactive lesion, a developmental anomaly or a benign neoplasm. The incidence of CGCG in the general population is estimated to be 0.0001%, with 60% of cases occurring before the age of 30 years. CGCG found more commonly in females and more commonly involve mandible as compared to maxilla, with an epicentre anterior to first molars. This paper presents a rare case of CGCG in a 52 year old female patient involving region posterior to mandibular first molar. As there is paucity in the literature about the CT findings of CGCG, we are presenting a case of CGCG with special emphasis on CT findings, in addition to clinical, histopathological and surgical aspect of the lesion.