1Assistant Professor, Department of Pharmacognosy, Faculty of Pharmacy, M.S. Ramaiah University of Applied Sciences
2Professor, Department of Pharmacology, Kamalakshi Pandurangan College of Pharmacy, Tiruvannamalai, Tamilnadu
3Professor and HOD, Department of Pharmacognosy, Faculty of Pharmacy, M.S. Ramaiah University of Applied Sciences
*Corresponding Author Email: gowri.pc.ph@msruas.ac.in
Online published on 18 January, 2019.
To evaluate the in vitro anti-inflammatory activity of methanolic and aqueous extracts of Polygonum barbatum leaves by human RBC membrane stabilization method.
The methanolic and aqueous extracts of leaves of Polygonam barbatum were prepared by continuous hot percolation and maceration method respectively.
The preliminary phytochemical screening was carried out for ethanol and aqueous extracts. The prevention of hypo tonicity-induced HRBC membrane lysis was taken as a measure to determine the anti-inflammatory activity of the extracts
In HRBC membrane stabilization method, both the extracts showed significant membrane stabilization effect and their anti-inflammatory activity was comparable to that of the standard drug Diclofenac sodium.
Polygonum Barbatum, Methanolic Extract, Aqueous Extract, HRBC Membrane Stabilization
