1Assistant Professor, Department of Pharmacy Practice, Faculty of Pharmacy, M.S. Ramaiah University of Applied Sciences, Bangalore-54
2Pharmacy Practice Students, Department of Pharmacy Practice, Faculty of Pharmacy, M.S. Ramaiah University of Applied Sciences, Bangalore-54
3Professor, Department of Endocrinology, M.S. Ramaiah Hospitals, Bangalore-560054
*Corresponding Author E-mail: mamatha.pp.ph@msruas.ac.in
Online published on 18 January, 2019.
The present study was conducted to analyzethe prescribing pattern of anti-diabetics and to assess incidence of adverse drug reaction (ADR) in diabetic population at our hospital setting.
An observational study was conducted on Type 2 diabetes mellitus patients on oral antidiabetic agents, attending Tertiary Care Hospital in Bangalore between November 2015 and April 2016. Patient demographics, pattern of prescription including details of adverse event history, were recorded in ae-designed data collection form. The causality relationship was assessed by the World Health Organization-Uppsala Monitoring Centre criteria.
A total of 52.67% of patients received Oral Hypoglycemic agents alone. The incidence of adverse drug reactions (ADRs) amongst the study population was found to be 33.33%. Males experienced majority of ADRs (54%) followed by females (46%). Major ADRs included hypoglycemia (54.23%) followed by giddiness (10.17%) and weight loss (8.47%). The prescribing pattern of anti-diabetics was to be in line with recommendations by American Diabetes Association.
Early detection and management of ADRs along with constant monitoring and active intervention ensures patient safety and better prognosis.
Diabetes, Adverse Drug Reaction, Oral Hypoglycemic Agents
