Protective effect of Omega-3 fatty acids on blood lipid profile of cigarette smoke exposed rats

The present study is undertaken to investigate the role of Omega-3 fatty acids on blood lipid profile viz serum cholesterol, serum triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL), and very low density lipoprotein (VLDL) in cigarette smoke exposed albino rats. Experimental rats (100-158g) were kept in standard laboratory conditions and grouped into three sets – control set A exposed to ambient air, experimental set (B) was exposed to cigarette smoke for one hour per day for 28 days and experimental set (C) was exposed to cigarette smoke with pre-exposure supplementation of Omega-3 fatty acids. A significant decrease in serum cholesterol (p<0.05), serum triglyceride (p<0.05), LDL (p<0.05) and VLDL (p<0.05) with a significant increase in HDL level (P<0.05) after supplementation of Omega-3 fatty acids in comparison to cigarette smoke exposed albino rats.