Journal of Ecophysiology & Occupational Health
  • Year: 2011
  • Volume: 11
  • Issue: 3and4

Assessment of cadmium induced alteration in superoxide dismutase and catalase activities of Labeo rohita (Hamilton, 1822)

  • Author:
  • Anurag Dabas, N. S. Nagpure, R. M. Mishra1, Ravindra Kumar, Basdeo Kushwaha, Rashmi Srivastava
  • Total Page Count: 7
  • Page Number: 205 to 211

1Department of Environmental Biology, Awadhesh Pratap Singh University, Rewa, Madhya Pradesh, India

Molecular Biology and Biotechnology Division  National Bureau of Fish Genetic Resources  Canal Ring Road, P.O. Dilkusha, Lucknow – 226 002 (UP), India

*E-Mail: nagpurens@yahoo.co.in

Online published on 21 July, 2012.

Abstract

The present study investigated the effects of cadmium chloride on the activities of antioxidant enzymes, viz. superoxide dismutase (SOD) and catalase (CAT), in liver and kidney tissues of cyprinid fish, Labeo rohita. The test specimens were exposed to three concentrations of cadmium chloride namely, 33.55, 67.09 and 100.64 mg L−1, for 96 h duration. A significant elevation in SOD activity and reduction in CAT activity was observed in a dose- and time-dependent manner in both the tissues. The results suggest the essential role of SOD and CAT in antioxidant defense system for protecting fish species from oxidative stress; hence, it can be considered as a sensitive biomarker of the antioxidant defense system.

Keywords

Antioxidant enzymes, Cadmium, Labeo rohita, Oxidative stress