Mosquito larvicidal efficacy of methanolic extract from seeds of Datura inoxia Mill against Aedes aegypti (Linn.) with insight into GC-MS analysis

The GC-MS analysis revealed the presence of 38 components, the major chemical constituents in the extract were atropine (20.55%), cis-13, 16-docasadienoic acid (19.73) n-hexane (15.67%), 1-chloro-1-fluoro ethane (6.84%), 9, 12-octadecadienoic acid (5.10%), lup-20(29)-en-3-ol, acetate (5.01%), scopolamine (2.87%). Bioassay experiments using methanolic extract from seeds of Datura inoxia Mill showed significant larvicidal activity against third instar larvae of Aedes aegypti with LC₅₀ and LC₉₀ values of 72.44 and 275.42 ppm, respectively.