A histological study of AgNPs activity against mosquito larvae Culex quinquefasciatus Say, 1823 (Diptera: Culicidae)

The recent development of nanotechnology is paving way for inventions to mitigate mosquito menace. Plant mediated Silver Nanoparticles (AgNPs) are one of such promising alternatives for synthetic pesticides, which are basically biodegradable substances. Various plant-mediated AgNPs have shown tremendous impact as mosquito larvicides. This study is aimed to understand the activity of AgNPs against Culex quinquefasciatus larvae. The histological study of mosquito larvae exposed to AgNPs has revealed that, the AgNPs are passing through various biological barriers and reaching on to the target sites. Binding of AgNPs with an antioxidant and detoxifying enzymes, may lead to significant oxidative stress in test organisms and may cause cell death. As a consequence, epithelial cells were separated from the basement membrane of the midgut and result were death of larvae.