1Quantum University Research Center, Quantum University, Roorkee - 247 667, Uttarakhand, India; Orcid Id : 0009-0008-4449-6366
2Centre of Research Impact and Outcome, Chitkara University, Rajpura - 140 417, Punjab, India; Orcid Id : https://orcid.org/0009-0000-4917-9337
3Chitkara Centre for Research and Development, Chitkara University, Solan - 174 103, Himachal Pradesh, India; Orcid Id : https://orcid.org/0009-0004-2848-0859
4Department of Biotechnology, Noida International University, Greater Noida, Gautam Budh Nagar - 201 310, Uttar Pradesh, India; Orcid Id : 0000-0002-6414-9731
Centre for Multidisciplinary Research, Anurag University, Hyderabad - 500 088, Telangana, India
*Corresponding authors’ E-mail : rapakasudhir@proton.me, Orcid Id : 0009-0005-0503-4239
Online Published on 13 May, 2025.
This study explores the genomic underpinnings of insect metamorphosis, providing insights into the complex developmental pathways that govern this transformative process. By integrating genomic technologies with classical developmental biology, we elucidate the genetic and molecular mechanisms that orchestrate insect growth and development. These findings demonstrate that key genes, such as those involved in ecdysteroid signaling and juvenile hormone regulation, play critical roles in determining the fate of insect tissues during metamorphosis. Comparative genomic analyses across different insect species uncover evolutionary trends in developmental strategies, while case studies on model organisms like Drosophila melanogaster and Bombyx mori illustrate the applicability of these insights to broader biological questions.
Development, Ecdysone, Evolutionary, Genomics, Gene regulation, Juvenile hormone, Metamorphosis, Model organisms, Signaling, Transcriptomics
