1Department of Biotechnology and Microbiology, Noida International University, Greater Noida, Gautam Budhha Nagar - 201 310, Uttar Pradesh, India, E-mail: shilpy.singh@niu.edu.in
2Department of Genetics and Plant Breeding, Institute of Agricultural Sciences, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar - 751 030, Odisha, India, E-mail: asitdash@soa.ac.in
3Department of Entomology, College of Agriculture, Parul University, Vadodara - 391 760, Gujarat, India, E-mail: mukesh.laichattiwar91094@paruluniversity.ac.in
4Department of Pharmaceutical Chemistry, Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth “Deemed to be University”, Karad, Satara - 415 539, Maharashtra, India, E-mail: ranjitjadhav705@gmail.com
Krishna Institute of Science and Technology, Krishna Vishwa Vidyapeeth “Deemed to be University”, Karad, Satara - 415 539, Maharashtra, India
*Corresponding authors' E-mail: aishwarya22999@gmail.com
Online published on 26 September, 2025.
Sustainable farming depends much on the management of pests since it guards crops and guarantees sufficient food for everybody. Older conventional methods and chemical pesticides sometimes harm the environment and result in pesticide resistant insect populations RNA interference (RNAi) as a potential new method of agricultural pest management employs short RNA molecules to turn off particular genes in pests, therefore reducing their numbers and causing the least possible damage to other living entities, RNAi presents a potential solution. Comparatively to other approaches, the study article examines various case studies demonstrating how well RNAi may be utilised to eliminate significant agricultural pests. Along with the methods RNA molecules are transported to pest species, there is discussion on the ways RNAi functions. Among the main unresolved issues still are RNA stability, off-target consequences, legal challenges, and popular acceptability. Although RNAi can entirely alter the way pests are controlled, the issues that must be resolved before it can be applied are really crucial. RNAi can contribute towards making agricultural pest management more environmentally friendly and sustainable.
Agriculture, Biotechnology, Delivery resistance, Ecosystems RNAi, Gene silencing, Non-target, Pest management, Public perception, Sustainability
