1Amrita Institute of Medical Sciences & Research Centre, Cochin.
2Aligarh Muslim University, Aligarh.
Genome organization of the human DNA has shown polymorphic variation at thousands of sites, which reflects an absolute genetic uniqueness for each individual. This unique feature of the genome has proved valuable, not only for convicting felons and exonerating the innocent, but also for establishing maternity or paternity and proving family relationships. The main methodologies in current use to investigate human DNA polymorphism have been discussed in this paper.
DNA markers, DNA fingerprinting, DNA analysis, RFLP, VNTR, mitochondrial DNA, Y chromosome, HLA complex, minisatellite, microsatellite
