Journal of Forensic Medicine and Toxicology
SCOPUS
  • Year: 2025
  • Volume: 42
  • Issue: 4

A Deadly Hotel Fire Incident: Case Series Of Carbon Monoxide Poisoning And Literature Overview

  • Author:
  • M Senthil Kumaran1,*, Sundaragiri Suraj2, Narsareddy Laxmikanth Reddy3, J Venkatesh4, Utsav Parekh5
  • Total Page Count: 6
  • Page Number: 99 to 104

1Associate Professor & In-Charge HOD, Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, Madurai, Tamil Nadu

2Assistant Professor, Department of Forensic Medicine and Toxicology, Gandhi Medical College, Secunderabad, Telangana

3Assistant Professor, Department of Forensic Medicine and Toxicology, Gandhi Medical College, Secunderabad, Telangana

4Associate Professor, Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, Kalyani, West Bengal

5Associate Professor, Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, Rajkot, Gujarat

*Corresponding author. E-mail address: drsenthilkumaran84@gmail.com (Dr. Senthil Kumaran M)

Online published on 12 March, 2026.

Abstract

Carbon monoxide (CO) poisoning is a significant global public health concern, often resulting in severe health consequences or fatalities. This report examines eight fatal cases of CO poisoning caused by a hotel fire, highlighting the complexity of CO exposure in fire-related incidents. The fire, originated in a basement used for commercial purposes and fueled by flammable materials. It rapidly escalated, causing widespread panic and trapping guests due to a sudden power outage. Post-mortem examinations revealed that all victims exhibited characteristic signs of CO poisoning, including cherry-red discoloration of tissues, soot in the respiratory tract, and elevated carboxyhemoglobin levels. Histopathological analysis of lung tissues showed congestion and black pigmentation, consistent with CO exposure. Chemical analysis confirmed significant CO levels in the victims’ blood. This incident underscores the critical need for stringent fire safety measures, including proper use of building spaces, functional emergency lighting, smoke detectors, and regular safety inspections. The findings demonstrate that CO poisoning, combined with smoke inhalation, is often more lethal than burns alone. The study reveals important features in cases of CO poisoning and also emphasizes the need for stricter adherence to fire safety regulations and improved safety protocols to prevent similar tragedies in the future.

Keywords

Carbon monoxide (CO), CO poisoning, Carboxyhemoglobin (COHb), Fire incident