* Dept of Pathology, Midnapore Medical College, Paschim Medinipur, West Bengal. mallikapatho@gmail.com
** Dept. of Pathology, Midnapore Medical College, Paschim Medinipur, West Bengal
*** Dept. of Forensic and State Medicine, Institute of Postgraduate Medical Education and Research, Kolkata.
**** Dept. of Forensic and State Medicine, Institute of Postgraduate Medical Education and Research, Kolkata.
***** Dept. of Forensic and State Medicine, N.R.S. Medical College, Kolkata.
There are more than 3000 species of snakes in the world but only about 350 are venomous. With approximately 10000 deaths occurring annually in India, a large proportion of snake bites occur when people work barefoot in the fields OT while walking at night or early morning through fields or along roads.
Although, nearly all snakes with medical relevance can induce nephropathy, leading to Acute Renal Failure (ARF), it is unusual except with bites by Russell's Viper, E. Carinatus and members of the genera Crotalus and Bothrops. In India, ARF is mostly associated with Russell's Viper and E. Carinatus bites. The incidence of ARF following Russell's Viper or E. Carinatus bites is 13–32% in India.
A histopathological study was conducted on renal autopsy specimens from those subjects who were admitted to IPGME&R and SNP Hospital, Kolkata as a result of development of acute renal failure following poisonous snake bite. Acute tubular necrosis (100%) and Acute cortical necrosis (25%) were the most significant renal histopathological changes. Glomerular lesions were also present in 30% of cases.
Snake Bite, Renal Histopathological Change, Acute Tubular Necrosis, Cortical Necrosis, Acute Renal Failure
