Journal of Indian Academy of Forensic Medicine
  • Year: 2014
  • Volume: 36
  • Issue: 1

Estimation of Time Passed Since Death by New Biochemical Parameters: MDA (Malondialdehyde) and Total Thiol

  • Author:
  • Sanchita Das Kundu1, Apurba Biswas2, Abhishek Das3, Anindya Kumar Goswami4, Parvind Kumar Singh4, Prabhas Chandra Chakraborty5
  • Total Page Count: 2
  • Page Number: 38 to 39

1Assistant Professor, Department of Forensic & State Medicine, Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal

2Assist. Prof, Dept. of Forensic & State Medicine, Maldah Medical College and Hospital, Maldah, WB

3Final year PGT, Dept. of Forensic & State Medicine, NRSMCH, Kolkata, West Bengal

4Assist. Prof, Dept. of Forensic & State Medicine, Sagar Dutta Medical College and Hospital, WB

5Prof & HOD, NRSMCH, Kolkata, West Bengal

Online published on 7 May, 2014.

Abstract

Determination of time passed since death is extremely important medico-legal issue. It requires meticulous examination, documentation and subsequent necessary evaluation by various pathological and biochemical examination. Two biochemical parameters, MDA breakdown product of lipid per oxidation and Total Thiol which is responsible for the protection of cells against oxidative stress are measured to estimate Time Passed since Death. Pearson correlation in various causes of death shows MDA level is significantly correlated with time passed since death, whereas Total Thiol level is inversely proportional. This study establishes role of MDA and Total Thiol as biochemical parameters to estimate time passed since death.

Keywords

Time passed since death, Biochemical parameters, MDA, Total Thiol. Causes of death