Department of Veterinary Microbiology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana-141004, (Punjab), INDIA.
*Corresponding author: Prof. H.M. Saxena, Flat No. 9, First Floor, Geetanjali Apartments, E-Block, Rishi Nagar, Ludhiana-141001, (Punjab), INDIA; E-mail: hmsaxena@yahoo.com
Infectious Bursal Disease (IBD) is an acute contagious disease of young chickens with high morbidity and low mortality causing heavy losses to poultry industry worldwide. The disease is caused by IBD virus (IBDV), an Avibirnavirus which infects immature bursal B-cells of young chicken. However, the target molecule of B cells for binding of IBDV is not known. This review attempts to discuss the various possibilities and the current research in this direction.
Infectious bursal disease virus, chicken B-cells, non-lymphoid bursal cells, B-cell differentiation, apoptosis
