Journal of Immunology and Immunopathology
  • Year: 2012
  • Volume: 14
  • Issue: 1

Immunomodulatory Effect of Gir Cow Urine Distillate in Rabbits

1Post Doctoral Fellow, Department of Cell Culture, G.B. Pant University of Agriculture and Technology, Patwadangar-263128, Nainital, Uttarakhand, India

2Post Doctoral Fellow, Department of Biopharmaceutical, G.B. Pant University of Agriculture and Technology, Patwadangar-263128, Nainital, Uttarakhand, India

3Senior Research Fellow, Department of Microbiology, G.B. Pant University of Agriculture and Technology, Patwadangar-263128, Nainital, Uttarakhand, India

4Campus Director Institute of Biotechnology, G.B. Pant University of Agriculture and Technology, Patwadangar-263128, Nainital, Uttarakhand, India

*Email id: joshi.ankita11@gmail.com

Abstract

In the present investigation, the immunomodulatory effect of distilled Gir cow urine was studied in rabbits for haematological parameters. The study revealed that the values of total leucocyte count (TLC), absolute lymphocyte count (ALC) and absolute neutrophil count (ANC) were significantly increased in Group II and the rabbits were given Gir cow urine distillate alone and Gir cow urine distillate with citric acid, respectively. By comparing the studies at the 60th day, there was an increase in total leucocyte count (TLC), absolute lymphocyte count (ALC) and absolute neutrophil count (ANC) levels in group II as 29%, 24.50% and 32%, respectively. In group III, an increase in total leucocyte count (TLC), absolute lymphocyte count (ALC) and absolute neutrophil count (ANC) levels were 49%, 41% and 49%, respectively. This clearly indicates the immunomodulatory effect of Gir cow urine alone and with citric acid.

Keywords

Gir Cow Urine, Total Leucocyte Count (TLC), Absolute Neutrophil Count (ANC), Absolute Leucocyte Count (ALC), immunomodulation