1Scientist, Project Directorate on Foot and Mouth Disease, IVRI Campus, Mukteswar, Nainital- 263138, Uttarakhand
2Asst. Professor, Department of Veterinary Medicine, College of Veterinary Sciences & Animal Husbandry (CAU), Selesih-796014, Aizawl, Mizoram
3Senior Scientist, Immunology Section, IVRI, Izatnagar- 243122, Bareilly, U.P.
*E-mail id: drsuvendu.kumar@gmail.com, drmrout@gmail.com
Online published on 29 July, 2013.
An auto-immune disorder is a malfunction of the body's immune system that causes the body to attack its own tissues. In other words, the body actually attacks its own cells. These maladies have posed a challenge to both clinicians and researchers ever since the nineteenth century. More than 80 auto-immune diseases (ADs) have been described till date. Some such as type 1 diabetes attacks specific organs, while others such as systemic lupus erythematosus involve multiple organs. Many inherent as well as other factors affect ADs. In modern days, many diagnostic and therapeutic approaches are available those can help to cure these deadly disorders. The present paper communicates in brief about the history, classification, various causes, mechanism, risk factors involved in auto-immune disorders and current developments in clinical as well as research field with respect to therapeutics and its prevention.
Auto-immune diseases, immune system, factors, symptoms, therapy auto-immunity, tolerance, classification of auto-immune diseases
