Journal of Immunology and Immunopathology
  • Year: 2013
  • Volume: 15
  • Issue: 1

Immunopathological Evaluation of Protective Potential of Cajanus indicus on Aflatoxin Induced Toxicity in Broilers

  • Author:
  • N Sahu, M Mondal, RC Ghosh, KM Koley
  • Total Page Count: 1
  • Page Number: 68 to 68

Department of Veterinary Pathology, College of Veterinary Science and A. H., Anjora, Durg (C. G.) -491001, India

*E-mail: drmondalmm@rediffmail.com

Online published on 19 December, 2013.

Abstract

Aflatoxins (AF), potent hepatotoxic and hepatocarcinogenic agents produced by fungus Aspergillus sp. are contaminants of feed ingredients frequently used for poultry rations. Hence, the present aim of study is to elucidate the protective potential of herb, Cajanus indicus on AFinduced immunopathological alterations in broilers. A total of 168 Vencobb day old broiler chicks were randomly divided into four equal groups of 42 each. Group I broilers were given plain feed and served as control whereas, group II and III were given Cajanus indicus leaf powder (CLP) @ 2 g/kg and AF @ 1 ppm with normal feed respectively. Group IV broilers were fed on diet containing AF @ 1 ppm and CLP @ 2 g/kg for 42 days. Aflatoxicosis significantly suppressed the both cell mediated and humoral immune responses. But CLP supplementation had a potent immunomodulatory effect. So, it helps not only in controlling aflatoxicosis but also can play a pivotal role in correcting chicken immune dysfunction.