1PhD Scholar, Graphic Era University, Dehradun
2Asstt. Prof., Graphic Era University, Dehradun
3Asstt. Prof., M.B.G.E., C.B.S.H., RAJUVAS, Bikaner
4C.V.A.Sc., RAJUVAS, Bikaner
5Assoc. Prof., In-charge, Animal Biotechnology Lab., V.P.B., C.V.A.Sc, G. B. Pant University of Agriculture & Technology, Pantnagar, Uttarakhand
6G. B. Pant University of Agriculture & Technology, Pantnagar, Uttarakhand
Online published on 19 December, 2013.
The term ‘Apoptosis’, after being coined in 1972 by Kerr, Currie and Wyllie to describe the common morphological changes that characterize the process of cellular self-destruction, has come a long way to become one of the most intensely studied cellular phenomenon. Apoptosis, the programmed or physiological cell death, plays an important role in embryogenesis, homeostasis, and certain pathologic events. Apoptosis has been characterized as a fundamental cellular activity to maintain the physiological balance of the body. It also plays a necessary and crucial role as a protective mechanism against carcinogenesis by eliminating damaged cells or abnormal excess cells proliferated. Emerging evidences have demonstrated that the anticancer activities of certain chemotherapeutic agents are involved in the induction of apoptosis, which is regarded as the preferred way to manage cancers.
