Journal of Immunology and Immunopathology
  • Year: 2015
  • Volume: 17
  • Issue: 2

Immune Responses to Haemonchus Contortus in Sheep

  • Author:
  • MK Vijayasarathi1,*, A Sheeba1, Manikkavasagan2, C Sreekumar3, K Dhama4
  • Total Page Count: 7
  • Published Online: Jun 1, 2015
  • Page Number: 79 to 85

1Department of Veterinary Parasitology, Madras Veterinary College, Vepery, Chennai-600007, Tamil Nadu, India

2College of Food and Dairy Technology, Koduvalli, TANUVAS, Chennai -600052, Tamil Nadu, India

3Post Graduate Research Institute in Animal Sciences, TANUVAS, Kattupakkam, Kancheepuram-603203, Tamil Nadu, India

4Division of Pathology, ICAR-Indian Veterinary Research Institute (ICAR-IVRI), Izatnagar, Bareilly-243122, Uttar Pradesh, India

*Corresponding author email id: sarathivet@gmail.com

Abstract

Sheep, called as ‘museum of parasites’, is susceptible to many nematodes. Among the nematodes, Haemonchus contortus is an important voracious blood sucking helminth, which causes alteration in pH of abomasum and blood parameters like PCV. The host produces some immune mechanism against H. contortus to limit the pathogenic effect produced by the parasite. However, the parasite escapes the host immune response in order to survive within the host, which is called ‘evasion’ mechanism.

Keywords

Haemonchus contortus, Immune response, Antigen, Immunoprophylaxis, Evasion, Sheep, Pathogensis