Immunopathological Effects of Nano Alumina on Humoral Immune Response in White Leghorns Chickens

Kuntal N, Agarwal S and Chauhan RS (2020). Immunopathological Effects of Nano Alumina on Humoral Immune Response in White Leghorns Chickens. Journal of Immunology Immunopathology, 22(2): 183–186.

Nanostructures can enter the body through various routes such as intravenous, dermal, subcutaneous, intraperitoneal, inhalation or oral. They enter the cells of organs and remain there for unknown durations before getting excreted or leaving to other organs. Limited investigations have been carried on effect of nanoparticles on health of animals and man. Therefore, present study was designed to study the effect of alumina nano particles on humoral immune response in White Leghorns Cockerels. 40 chicks of two-week age were divided into two groups of 20 birds each viz. Group I (control) and Group II (treated). The treated group nano-alumin a used as aluminium oxide (Boehmite), was given orally in standard recommended feed at the rate of 200 ppm. Hu moral immune response was performed at 30 days interval taking samples from 10 birds from each group. The results in this study revealed an increase in humoral immune response but the results were not significant statistically.