1Ex PG Student, Department of Veterinary Microbiology, College of Veterinary Sciences & Animal Husbandry, DUVASU, Mathura-281001, Uttar Pradesh, India
2Associate Professor, Department of Immunology & Defense Mechanism, College of Biotechnology, SVPUAT, Meerut-250110, Uttar Pradesh, India
3Assistant Professor, Amity Center for Mycobacterial Disease Research, Amity University Rajasthan, Jaipur-303002, Rajasthan, India
4Principal Scientist, Division of Animal Health, ICAR-CIRG, Mathura-281122, Uttar Pradesh, India
5Professor, Department of Veterinary Microbiology, College of Veterinary Sciences & Animal Husbandry, DUVASU, Mathura-281001Uttar Pradesh, India
*Corresponding author email id: balyan74@gmail.com
Sharma AK, Kumar A, Sohal JS, Rahal A and Yadav SK (2020). Assessment of Antimicrobial and Immunomodulatory Activities of Hot Aqueous Extract of Calotopris procera Leaves. Journal of Immunology Immunopathology, 22(2): 187–196.
Calotopris procera, a widely used plant in traditional medicine almost throughout the world is now reported to have certain cancer-active constituents with molluscicidal, nematocidal, and insecticidal activities. However, plant activities are still to be scientifically validated for immunomodulation and antimicrobial activities. Thus, in the present study hot aqueous extracts (HAE) of Calotropis procera plant leaves were subjected to estimation of antimicrobial and immunomodulatory activities. The HAE of the plant revealed no antibacterial and antifungal activities. However, good antiviral and immunomodulatory activities were reported. These activities were in a dose-dependent manner and accordingly, dose decides the up and down regulation of anti-inflammatory activities. These findings produced promising results for future exhaustive study with active principles.
Calotopris procera, Antimicrobial activities, Antiviral activities, Immunomodulatory properties
