Beneficial Effect of Ajuga bracteosa with Special Reference to Immunomodulatory Effect: An Overview

Bisht R, Verma M, Sarah R and Kumar D (2020). Beneficial Effect of Ajuga bracteosa with Special Reference to Immunomodulatory Effect: An Overview. Journal of Immunology Immunopathology, 22(1): 83-91.

The therapeutic use of traditional medicine is gaining currency in the treatment of a variety of ailments. The untapped potential of many plants is yet to be explored as a source of medicine. The genus Ajuga has enormous medicinal and economic importance. There are almost 300 species of Ajuga notably; Ajuga bracteosa is an important medicinal plant that has many therapeutic properties as anti-microbial, anti-tumour, anti-plasmodial, antipyretic, anti-helminthic, anti-malarial, anti-inflammatory, hepatoprotective, immunomodulatory, cytotoxic and insect antifeedant. So far many active principles have been isolated from A. bracteosa such as neo-clerodane diterpenoids, flavonol glycosides, iridoid glycosides, ergosterol-5,8-endoperoxide and phytoecdysones. The present review aims to highlight the immunomodulatory role of A. bracteosa besides their other pharmacological roles.