Journal of Immunology and Immunopathology
  • Year: 2021
  • Volume: 23
  • Issue: 1

Antimicrobial Profile of Clostridium perfringens Isolates from Milk and Milk Products

  • Author:
  • Sujata Meravi1, R.V. Singh2, Gupta Bhavana3, Vijaya Singh Thakur1, Jadav Kajal Kumar4
  • Total Page Count: 5
  • Published Online: Mar 9, 2022
  • Page Number: 11 to 15

1MVSc, Department of Veterinary Public Health & Epidemiology, College of Veterinary Science & Animal Husbandry, NDVSU, Jabalpur-482001, Madhya Pradesh, India

2Professor & Head, Department of Veterinary Public Health & Epidemiology, College of Veterinary Science & Animal Husbandry, NDVSU, Jabalpur-482001, Madhya Pradesh, India

3Assistant Professor; Department of Veterinary Public Health & Epidemiology, College of Veterinary Science & Animal Husbandry, NDVSU, Jabalpur-482001, Madhya Pradesh, India

4Assistant Professor, Animal Biotechnology Centre, NDVSU, Jabalpur-482001, Madhya Pradesh, India

*Corresponding author email id: rvsvet24oct@gmail.com

Online published on 9 March, 2022.

Abstract

The aim of the present study was to observe the antimicrobial profile of 21 isolates of C. perfringens from 250 samples of milk and milk products from Jabalpur city. Isolates were subjected to antimicrobial susceptibility test using disc diffusion technique. In vitro antimicrobial assay against 16 antibiotics revealed that isolates were sensitive to ciprofloxacin (95.23%), ofloxacin (76.19%) and vancomycin (61.90%) and isolates were resistant to amoxicillin (76.19%), ceftazidime (71.42%) and co-trimoxazole (47.61%). The isolates displayed multidrug and Multiple antibiotic resistance (MAR). The MAR index for different isolates revealed that 15 (71.42%) isolates have MAR index greater than 0.2 and 6 (28.57%) isolates have less than 0.2. The higher resistance of C. perfringens isolates towards amoxicillin, ceftazidime and co-trimoxazole is of great concern as these antimicrobials are commonly used in therapeutic management.

Keywords

Antimicrobial, Isolates, C. perfringens, Milk, Milk products