Relationship between vitamin D levels and various physiological parameters among the adult males of Chandigarh, India

Vitamin D deficiency may be linked to elevated blood pressure because vitamin D has pleiotropic effects in various organ systems.

The objective of the present study is to assess the correlation of the various physiological parameters with the vitamin D level among the adult males of Chandigarh, India.

The sample included 332 males of the age ranging between 30 and 70 years. Vitamin D level of all the participants was estimated by employing chemiluminescence immunoassay method. All the subjects were divided into three categories of Vitamin D level, i.e., normal range (>30–100 ng/ ml), insufficiency (21–29 ng/ml), and deficiency (0–20 ng/ml) as per the Endocrine Society Guidelines (2011). Hypertension was defined as Systolic Blood Pressure (SBP) ≥140 mmHg, or Diastolic Blood Pressure (DBP) ≥90 mmHg (WHO guidelines, 2021).

Systolic blood pressure was found to be positively (r=0.032, p>0.05) and non-significantly correlated with vitamin D levels in the males present in vitamin D normal category. However, diastolic blood pressure was negatively (r=-0.142, p<0.05) and significantly associated with the vitamin D level in males lying in normal category of vitamin D.

The systolic blood pressure, diastolic blood pressure and pulse rate were negatively and non-significantly associated with the vitamin D levels among the males in the vitamin D deficient category.