Assistant Professor, Department of Zoology, Dr. Sarvepalli Radhakrishnan Government Degree CollegeDharampur, Mandi-175040, Himachal Pradesh, India
Online Published on 04 September, 2024.
Proteolytically controlled events are essential to apicomplexan parasites because of their intricate life cycles. Throughout the whole life cycle of a parasite, proteases play specific roles. With an emphasis on three crucial biological events: host-cell invasion, haemoglobin degradation, and host-cell rupture. This review offers the most recent information on the proteases in Plasmodium species. The intricate processes that are centrally controlled by proteases are now well-understood - developments in the study of parasite biology. The foundation for validating novel networks and enzyme targets that may be used as therapeutic targets to combat malaria is laid by these developments in our molecular understanding of the proteolytic events involved in parasite pathogenesis.
Plasmodium, Malaria, Proteases, Invasion, Haemoglobin degradation, Egress