Evaluation of the Effects of a Traditional Combined Ointment on Healing Process of Burn Wounds in Comparison to Silver Sulfadiazine

Burning is one of the most common types of trauma that people encounter with every day of their lives. A lot of researches have been done on finding the best and the most effective curing method. There are still different opinions among traditional and new modern techniques in this relation. The purpose of this paper is to determine the healing effects of a traditional ointment consist of olive oil, sheep fat, honey wax, turmeric, salt, henna, yolk, and, Saqqez (natural gum) on grade II burned wounds healing in mice and a comparison of that with silver sulfadiazine (SSD) as an effective agent in this relation. 45 male mice were anesthetised and burned in 90oc for 10 seconds by a device which regulated for making grade II burns. Then samples divided into three groups (normal saline group, SSD group and compound ointment group) randomly and cured daily. Results documented in 3 days (Days 0, 7 and 14). Half of the mice were selected for histopathological, morphometric assessment and wound size changes on Day 7, and the rest of them remained for the same assessments on Day 14. The microscopic and macroscopic evaluations showed that the compound ointment had the same effect on decreasing the inflammation and increasing the healing process as SSD cream compared to the control group. There were no significant morphological differences between these two treatment groups. The current study shows that although the compound ointment had better results than the control group, there was not a significant difference between the compound group and the SSD group in a healing process. It has to be noted that the antibacterial effect of this ointment was not noticeable in comparison with SSD. There was not any significant effect of this compound on the sizes of the wounds during the experiment. It seems that the only factor affecting the size of the wound in all groups is the time. Overall, the traditional ointment’s potential in promoting burn wound healing underscores the significance of exploring natural remedies and traditional medicine practices in healthcare.