Journal of Immunology and Immunopathology
  • Year: 2024
  • Volume: 26
  • Issue: 2

Analysis of lipid profile variations in type 2 diabetes patients pre and post COVID-19: Insights from Pathankot

Research Scholar, Department of Biochemistry, Desh Bhagat University, Mandi Gobindgarh, Punjab, India

*Corresponding author email id: yuvrajrai1608@gmail.com

Online published on 13 June, 2025.

Abstract

This research sought to examine differences in the lipid levels of adults with T2DM after COVID-19 contraction. Knowledge of such changes is important to prevent metabolic disorders and enhance the management and outcome following infection. This paper presents a cross-sectional survey done between March and September 2023 with 200 adults, 18 to 45 years old, from Pathankot, Punjab. Cholesterol levels, triglycerides, LDL, HDL, and HbA1c were taken after recovering from COVID-19 infection. Descriptive statistics were used to estimate the overall average of the different variables and to look for outliers. Metabolic disorders were evident to have affected the patient highly after contracting COVID-19, according to the study. Elevated levels of LDL (mean: 188.Systolic blood pressure was also significantly higher (mean 139.67 mmHg) with an increase in both total cholesterol (mean 24 mg/dL) and triglycerides (mean 151.53 mg/dL) with a decrease in the HDL cholesterol (mean 43.79 mg/dL). Further, HbA1c levels showed poor glycaemic control, evidencing the fact that these patients were experiencing aggravated metabolic stress. These findings underscore the need for close periodic follow-up and metabolic control in T2DM patients who have been infected with COVID-19. It appears that lifestyle changes, as well as specific prevention initiatives, may be required to prevent or control long-term risk factors. However, more needs to be done to establish how the observed changes work in practice.

Keywords

Type 2 diabetes mellitus (T2DM), Lipid profile, COVID-19, Obesity, Lifestyle