College of Veterinary Sciences, G.B. Pant University of Agriculture and Technology, Pantnagar - 263 145, (Uttaranchal).
Immunomodulation is manipulation of immune system and is characterized either by immunosuppression or immunopotentiation. During changing environmental scenario, a state of acquired immunodeficiency occurs including decreased humoral and cell mediated immune response to a vaccine and or infection. As most of the antibiotic drugs are bacteriostatic, they check the growth of bacteria which are to be killed through phagocytosis by phagocytic cells. The activity of phagocytic cells is not properly maintained in body as a result of polluted feed, air and water. It is therefore, necessary to augment the phagocytic activity of the macrophages through immunomodulation in order to check the recurrent infections, occurrence of new disease outbreaks and cancers. Various aspects of immunomodulation, immunomodulatory molecules and mechanism of action and their relation with nervous system is described.
Immunopotentiation, mechanism of action, immunomodulatory molecules, neuroimmunomodulation, herbal immunomodulation, cow therapy
