1Department of Electrical Engineering, Indian Institute of Technology, Kanpur-208 002, (U.P.).
2Immunology Lab, Department of Pathology, GSVM Medical College, Kanpur-208 002, (U.P.).
The present study explores the untoward effects of acute high power density microwave radiation (MWR) at 100 mw/cm2, 2.1 GHz on humoral and cell mediated immune responses of 12 Belgian white male rabbits exposed for 45 minutes, followed by 48 hours and 7 days in miniature anechoic chambers. Blood collected at the termination of MWR was analyzed for T-cell mediated immune response mechanism counting T lymphocytes percentage and their mitogen responsiveness to Con A (10μg) and PHA (4μg) and b-cell mediated immune response mechanism by counting B lymphocyte percentage using Ig+B lymphocyte estimation by FITC tagged anti-rabbit immunoblonulin, IgG and IgM evaluation via SRID and serum protein estimation by SDS-PAGE. No significant changes were observed in humoral immune response, B lymphocytes counts, Immunoglobulins level, serum protein values, (significant level is p> 0.05 in all cases) when compared with sham exposed control groups of rabbits, except temporary changes in T lymphocytes (p<0.0025) counts. Hence we conclude that acute high power density microwave radiation does not produces any specific immune alteration.
Immunity, rabbits, microwave radiation
