Division of Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar, Bareilly-243 122 (Uttar Pradesh), INDIA.
*Corresponding author: E-mail: raia1@rediffmail.com
The VP2 capsid protein of canine parvovirus has different groups, which show the reactive sites on the protein. When various parameters were applied in the Swiss-model software, different groups like strand color group, ball and stick color group, ribbon color group, space-fill color group, wire frame color group could be seen. These model features showed clearly the reactive sites as well as grooves on the protein. The three dimensional protein structures are essential for the proper understanding of the molecular basis of protein function. Since VP2 is responsible for neutralizing antibody which gives protection, the epitopes groups seen in the model structure could be the antigenic sites for neutralising antibody.
Canine parvovirus, VP2 capsid protein, modeling