Immunological characterization of Salmonella cytotoxins

Salmonellosis remains a major food borne zoonosis affecting both man and animals. Foods of animal origin are most common source of infection to man. Although salmonellae have multifactorial pathogenesis, but the role of toxins (enterotoxins and cytotoxins) produced by them is significant in causing gastroenterstinal disorders. In present study attempts were made to find genus specific proteins of Salmonella and to study cytotoxic effects of cytotoxic preparations of Salmonella on BHK 21 cells. It was also aimed to standardize polyclonal ELISA based test for detection of Salmonella in foods of animal origin.