Journal of Innovation in Pharmaceutical Sciences

  • Year: 2018
  • Volume: 2
  • Issue: 2

Exploring Ziziphus Sps fruit mucilages as a pharmaceutical excipients in Novel Drug Delivery Systems

  • Author:
  • Gugulothu Dalapathi, Choudhary Suraj Kumar
  • Total Page Count: 5
  • DOI:
  • Page Number: 17 to 21

Balaji Institute of Pharmaceutical Sciences, Laknepally (Village), Narsampet, Warangal Rural, Telangana, India-506331

*Correspondence to: Dalapathi Gugulothu, Department of Pharmaceutics, Balaji Institute of Pharmaceutical Sciences, Laknepally (V), Narsampet (M), Warangal (D), Telangana State, India.-506331, Email: dalugugulothu@gmail.com

Online published on 27 September, 2019.

Abstract

Recent trends towards the use of natural mucilages demand the replacement of synthetic additives with natural ones. Today, the entire globe is showing interest on natural drugs and excipients as of their chemically inert, biocompatible, biodegradability, non-toxic, economic, eco-friendly and commonly available. In the present work we have extracted the mucilages from Ziziphus mauritiana and Ziziphus jujuba fruits and evaluated for loss on drying, pH, swelling index, viscosity studies, bioadhesive strength, powder micromeritics properties, FTIR, DSC and XRD study and finally compared with the synthetic polymers (HPMC K4M CR, HPMC K15M CR, Na CMC and Carbopol® 974).The evaluation results of the above extracted mucilages are exhibited like synthetic polymers in case of micromeritics, bioadhesive strength and viscosity studies. Finally, it was concluded that the extracted mucilages were used as excellent pharmaceutical additives and good replacement for synthetic polymers.

Keywords

Bioadhesive strength, mucilages, XRD and Ziziphus.