Assessment of the diuretic and urinary electrolyte effects of ethanolic extract of flowers of Capparis Decidua

Diuretics are the agents which increase the amount of urine flow and sodium excretion and are used to adjust the volume and/or composition of body fluids in a variety of clinical situations, including hypertension, cardiac failure, kidney failure, nephrotic syndrome, and cirrhosis. These agents were widely explored in Indian ancient system of medicine. The numerous diuretic plants with their active phytoconstituents have been explored. The present study was carried out to investigate the diuretic activity of ethanolic extract of flowers of Capparis decidua. Lipschitz test in Wistar rats was used to evaluate the diuretic effect of ethanolic extract of Capparis decidua. with furosemide as a standard and normal saline as control. The urine volume (in mL) measured at 5 h. The urine volume and urinary electrolyte excretion (Na+ and K+) were found to be significantly higher in rats treated with Capparis decidua. as compared to normal rats. This present study indicates that Ethanolic extract of flowers of Capparis decidua. has potential diuretic and natriuretic property.